Dejerine-Roussy syndrome: ________

Alkalization of urine by giving bicarbonate is used to treat patients presenting with phenobarbital (weak acid) overdose. Which of the following best describes the rationale for alkalization of urine in this setting?

A. To reduce tubular reabsorption of phenobarbital. B. To decrease ionization of phenobarbital. C. To increase glomerular filtration of phenobarbital. D. To decrease proximal tubular secretion. E. To increase tubular reabsorption of phenobarbital.

A patient is admitted to the intensive care unit with a closed head injury sustained in a motorcy-cle accident. The injury has caused severe damage to the posterior pituitary. Which of the fol-lowing complications should the nurse anticipate?

a. Dilutional hyponatremia b. Dehydration from polyuria c. Cardiac arrest from hyperkalemia d. Metabolic acidosis