The myeloid-to-erythroid (M:E) ratio of a bone marrow is 1:1. Select the correct interpretation
a. Normal
b. Abnormal, more fat cells than normal
c. Abnormal, more white cell precursors than normal
d. Abnormal, more red cell precursors than normal
ANS: D
The normal M:E ratio of bone marrow is 1.5:1 to 3.3:1. A ratio of 1:1 is therefore decreased, meaning that either the number of red cell precursors has increased or the number of white cell precursors has decreased. The fat-to-cell ratio assesses the overall cellularity of the marrow and should be roughly 1:1.
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