You are out to dinner with your friend who is in her second trimester of pregnancy. You order a beer and she proceeds to order a glass of wine

When you raise a concern about alcohol being dangerous for the developing fetus, she replies, "My doctor told me it was okay to have a glass of wine once in a while." What is your evaluation of this advice?
What will be an ideal response?

No safe amount of alcohol has been determined during pregnancy. Even a few drinks can put a developing fetus at risk for lower height, weight, and head size and heavy drinking causes FASD. There is a dose-response relation between alcohol and negative effects.