Drugs that are weak bases (e.g., erythromycin, codeine, and morphine) are more lipid soluble and have greater absorption in the small intestine
Indicate whether the statement is true or false
T: Drugs that are weak will be more nonionized (nonpolar) at the pH of the basic small intestine (pH 6-7) and ionized, more polar, and more water soluble in the stomach. The nonionized portion of the drug shows great lipid solubility and therefore greater absorption in the small intestine.
Health Professions