_____ develops with the use of benzodiazepines

Fill in the blank(s) with correct word

Tolerance: Tolerance does occur within 3 to 14 days whereby more and more of the drug is needed to get a therapeutic response. Because of this, overdosing is also less likely to occur. Dependence is most likely to occur in patients with a past history of alcoholism or substance abuse. However, if taken for prolonged periods of time (even normal doses), dependence may occur as soon as 4–6 weeks of starting the drug.