For which of the following drugs may toxicity occur when blood levels of potassium are lower than normal?
A) digoxin
B) cortisol
C) tetracycline
D) morphine
A) digoxin
For digoxin, toxicity may occur when blood levels of potassium are lower than normal. This is a highly significant example of altered drug response due to electrolyte imbalance. Lower than normal levels of potassium may result in digoxin toxicity, and potentially fatal dysrhythmias.
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