Which of the following would be appropriate initial testing for the siblings in Question 1?
a. Fibrinogen, D-dimer, and platelet aggregation studies
b. Factor VIII assay, liver function tests, and vitamin K level
c. von Willebrand factor (VWF) antigen, Bethesda titer, and reptilase time
d. Prothrombin time (PT), partial thromboplastin time (PTT), and platelet count
ANS: D
The initial hemostasis profile should consist of the PT, PTT, and platelet count.
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