Describe subchondral bone. Explain how OA affects the subchondral bone
What will be an ideal response?
The word chondral refers to cartilage. Subchondral bone is that portion of bone that sits just below the cartilage. As OA progresses, subchondral bone stiffens and undergoes infarction. Cartilage breaks down and is gradually destroyed. Bone-on-bone contact develops in advanced disease. Without the protection of the cartilage, cysts, scar tissue, and osteophytes form at the joint margins
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