In order to destroy prions, such as those in Creutzfeldt-Jakob disease, how long must they be sterilized?

a. Chemically sterilized for 10 minutes in Cavicide
b. Steam sterilized for a minimum of 1 hour at 270° F after soaking in sodium hydroxide for 1 hour
c. Soaked in ethylene oxide for at least 30 minutes, then dry heat sterilized for 10 minutes
d. Rinsing in sterile water at 240° F for 1 hour then rinsing in Cavicide

ANS: B
Prions are an infectious protein that must be steam sterilized for a minimum of 1 hour at 270° F after soaking in sodium hydroxide at room temperature for 1 hour. If a prevacuum sterilizer is used, the item can be processed for 18 minutes at 274° F after soaking for 1 hour in sodium hydroxide.

Health Professions

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