Discuss how you might investigate one personality problem with an eye to using positional cloning to prevent that problem

What will be an ideal response?

Answer: Positional cloning is a process by which a given gene can be altered by replacing either the whole gene or a portion of the gene to alter the result of the expression of that particular gene. If we targeted one personality factor, say the lack of empathy, which is associated with behaving badly to other people, we might be able to find the gene responsible for that particular personality characteristic. If we then identified an allele that correlated with high empathy and another correlated with being low in empathy and discovered the difference between the two, we might be able to either replace or alter the allele that correlates with low empathy. Hopefully this would make it more likely that the individual would have the functionality that makes it possible to understand and feel the emotions of others. [Obviously there are a host of hypothetical examples that a student might use to answer this question.]