The A1c modified component of Hb A is increased in what condition?
a. Sickle cell anemia
b. Thalassemia
c. Disorders of heme
d. Uncontrolled diabetes mellitus
ANS: D
Hemoglobin is a posttranslational modification of hemoglobin in which the hemoglobin molecule is glycated. Its concentration is increased when diabetes is uncontrolled.
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