Which of the following are examples of agonist-antagonists?
A) dobutamine and insulin
B) pentazocine and meperidine
C) norethindrone and dobutamine
D) antihistamine and naloxone
B) pentazocine and meperidine
Pentazocine and meperidine are examples of agonist-antagonists, which are agonists that produce weaker or less effective responses than endogenous chemicals. They are also known as partial agonists, and have only slight intrinsic activity. Pentazocine has much lower pain-relieving actions than a full agonist such as meperidine.
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Toxic nerve agents:
a. overstimulate the nerve endings and the central nervous system. b. block stimulation of sensory nerve endings only. c. decrease production of chemical transmitters. d. block stimulation of both sensory and motor nerve endings.
In contrast to the sympathetic nervous system, the parasympathetic nervous system:
A. prepares the body to handle stress. B. causes an increase in the heart rate. C. slows the heart and respiratory rates. D. dilates the blood vessels in the muscles.