Which of the following reasons best describes why it is advantageous to use a 25 gauge long needle for an IA nerve block?

A) Greater depth of penetration, less needle flexibility when contacting bone to determine deposition site, high risk of positive aspiration
B) Ease of penetration through fibrous submucusal tissues, greater depth of penetration, low risk of positive aspiration
C) Greater depth of penetration, greater accuracy of aspiration outcomes, less needle deflection
D) Comfort level during penetration, greater depth of penetration, low risk of negative aspiration

C