What establishes the capillary colloidal osmotic pressure?
a. Presence of electrolytes in plasma
b. Presence of plasma proteins in blood
c. Presence of RBCs in whole blood
d. Presence of WBCs in whole blood
ANS: B
Proteins such as albumin are too large to pass through the pores of the capillary. Instead, these proteins remain in the intravascular compartment and exert osmotic pressure, which draws water and small solute molecules back into the capillaries. This plasma colloid osmotic pressure is also sometimes called oncotic pressure. Because these large proteins are negatively charged, they at-tract (but do not bind) an equivalent amount of cations to the intravascular compartment. These cations have the effect of increasing osmotic pressure within the capillary (Donnan effect).
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