Explain the detection and significance of chimerisms in stem cell transplantation
What will be an ideal response?
The presence of chimerisms indicates complete infusion of donor HSCs into the recipient. The method of detection is through variable number tandem repeat (VNTR) polymorphisms, which separate out donor DNA/RNA from recipient DNA/RNA. Complete chimerisms exist if there is only donor DNA/RNA present. A complete chimerism indicates a successful stem cell transplant.
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Which of the following automatic sprinkler systems in continually charged with air or nitrogen under pressure?
A. Deluge sprinkler system B. Preaction sprinkler system C. Dry-pipe sprinkler system D. Wet-pipe sprinkler system
A slow onset of a low-grade fever and respiratory distress in a 3-year-old child is MOST characteristic of:
A: asthma. B: bronchitis. C: croup. D: epiglottitis.