Which of the following parameters are major factors in determining tissue oxygenation? 1. Arterial oxygenation 2. Tissue perfusion 3. Oxygen (O2) uptake 4. P/F ratio

a. 1 and 3 only
b. 1, 2, and 3 only
c. 3 and 4 only
d. 2, 3, and 4 only

ANS: B
Tissue oxygenation depends on inspired oxygen levels (FiO2), inspired partial pressure of oxygen (PIO2), alveolar oxygen tension (PAO2), arterial oxygenation (PaO2, SaO2, oxygen content of ar-terial blood [CaO2]), oxygen delivery (DO2), tissue perfusion, and O2 uptake.

Health Professions

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What is the best method of ventilation for a head-injured patient with signs of brainstem herniation?

a. hyperventilation with CO2 less than 35 mmHg b. hypoventilation with a CO2 greater than 45 mmHg c. hypo-oxygenation with an O2 saturation of 90 mmHg d. normal ventilation with a CO2 of 40 mmHg

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