Dr. Atchley is performing an autopsy on a brain of a patient who had Alzheimer's disease. What two cellular abnormalities would Dr. Atchley expect to find? What damage would these have done to the brain?
What will be an ideal response?
Dr. Atchley would expect to find amyloid beta plaques and tau tangles. The plaques are caused by an accumulation of the amyloid beta protein which damages axons and dendrites, decreases synaptic input, and decreases plasticity. The damaged axons and dendrites cluster into structures called plaques that damage the cerebral cortex, hippocampus, and other areas. Also, high levels of amyloid beta cause more phosphate groups to attach to tau proteins. The altered tau cannot bind to its usual targets within axons, and so it starts spreading into the cell body and dendrites.
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By age 5, the brain has reached ____ percent of its adult weight
Fill in the blank(s) with correct word
According to the “doctrine of ____________” different nerve fibers, regardless of what acts as a stimulus upon them, always produce a quality if experience specific to the sensory nerve.
a. neural localization b. specific nerve energies c. cerebral localization d. cerebro-neural pathway