Which of the following provides the best evidence that there is a difference between bipolar affective disorder and unipolar depression?

A) Chlorpromazine is only effective in treating unipolar depression.
B) There is a sex difference in the incidence of these disorders.
C) Lithium is effective in treating only bipolar disorder.
D) The age of onset differs between the two disorders.
E) Serotonin reuptake inhibitors are effective for bipolar disorder but not unipolar depression.

Answer: C
Rationale: The observation that lithium is effective in treating only bipolar disorder provides the best evidence that there is a difference between bipolar affective disorder and unipolar depression.

Psychology

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