Estrogen should not be given to women with:

A. diabetes insipidus
B. thyroid disease
C. breast cancer
D. stroke

c
Rationale: The estrogens are contraindicated in women with breast cancer and in those who are pregnant or lactating, and they should be used with caution if a patient has liver disease, gallbladder disease, endometriosis, pancreatitis, diabetes mellitus, heart failure, or kidney dysfunction.