The prototype nonselective ß-blocker is _____
Fill in the blank(s) with correct word
propranolol (Inderal): The prototype nonselective b-blocker is propranolol (Inderal). Its therapeutic effect is to decrease cardiac output and blood pressure, thus it is used in the treatment of hypertension. Since it decreases oxygen demand to the heart and produces peripheral vasoconstriction, it is used in the treatment of angina and tachycardia. Since it is a nonselective ß1-blocker, it will also block b2-receptors on the lungs, which may cause bronchoconstriction in asthmatics.
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