Describe the symptoms and causes of phenylketonuria and Tay-Sachs disease. How are these diseases related to one another?
What will be an ideal response?
Answer: Each of these diseases is an example of an inherited metabolic disorder. Phenylketonuria is an inherited lack of an enzyme that results in the buildup in blood of a toxic metabolite of phenylalanine (resulting in severe mental retardation). During a critical period of postnatal brain development, the PKU child is placed on a low phenylalanine diet. Tay-Sachs disease is a disease in which the lysosomes are unable to destroy certain cellular waste products, which accumulate to toxic levels.
You might also like to view...
Recent evidence suggests that paternal alcohol use around the time of conception
A) can cause fetal alcohol syndrome. B) has no negative effect on the developing organism. C) can cause alcohol-related neurodevelopment disorder. D) can alter gene expression.
When researching a hidden populations, investigators typically cannot use
a. techniques to reduce impression management. b. respondent-driven sampling. c. chain-referral methods. d. probability samples.