Upon receiving an order for a Schedule II controlled substance, a supplier notices that the quantity ordered has been altered. Which of the following statements is true regarding alterations of an official DEA order form for Schedule II drugs?

Any alterations to the order form must be reported to the DEA
Any signs of alterations on the order form may be enough to allow the supplier to refuse the Schedule II controlled substance order
Any alterations to the DEA order form result in the pharmacy's ability to order Schedule II medications being revoked
Any alteration of an order form is not enough for the supplier to refuse the Schedule II controlled substance order

Any signs of alterations on the order form may be enough to allow the supplier to refuse the Schedule II controlled substance order

Rationale: For schedule II drugs, any signs of alterations on the order form (222) may be enough to allow the supplier to refuse the order. The DEA's official wording states that "A DEA Form 222 must not be filled if the order is not complete, legible, or properly prepared, executed, or endorsed – or if the order shows any alteration, erasure, or change of any description.".