When Hb saturation with O2 is high, less carbon dioxide is carried in the blood. What is this rela-tionship called?

a. Bohr effect
b. Chloride shift
c. Dissociation constant
d. Haldane effect

ANS: D
Figure 12-14 shows that oxyhemoglobin saturation also affects the position of the carbon dioxide dissociation curve. The influence of oxyhemoglobin saturation on carbon dioxide dissociation is called the Haldane effect.