What are the major mechanisms responsible for maintaining a stable pH despite massive CO2 production? 1. Isohydric buffering 2. Gastrointestinal secretion 3. Pulmonary ventilation

a. 2 and 3 only
b. 1 and 2 only
c. 1, 2, and 3
d. 1 and 3 only

ANS: D
Isohydric buffering and ventilation are the two major mechanisms responsible for maintaining a stable pH in the face of massive CO2 production.