What counterarguments do proponents of animal research make in justifying their work?

What will be an ideal response?

Coile and Miller (1984) considered published research to investigate the claims of opponents to animal research and found that the claims of exposure to intense pain, starvation, and mutilation were not valid and were essentially nonexistent in psychological research.
In addition, Coile and Miller pointed out that experimental animals have produced useful treatments for such maladies as cancer and AIDS, and have helped us understand some aspects of the development of depression.