Immediately following the onset of cardiac arrest, brain cells begin to die after:

An 18-year-old, 5'6", 125 lb female patient was admitted to the hospital 2 days ago for spinal meningitis

She developed sepsis and suffered hypercapnic respiratory failure. The patient was intubated and placed on volume-controlled continuous mandatory ventilation (VC-CMV), respiratory frequen-cy (f) 12 breaths/min, tidal volume (VT) 600 mL, positive end-expiratory pressure (PEEP) 5 cm H2O, fractional inspired oxygen (FIO2) 0.40. Twenty-four hours later, the patient's oxygen re-quirements have dramatically increased and her lung compliance has dramatically dropped, while her chest X-ray showed development of bilateral fluffy infiltrates. The most appropriate actions to take include which of the following? a. Keep VT the same, increase f to 25 breaths/min, increase PEEP to 12 cm H2O. b. Decrease VT to 250 mL, increase f to 15 breaths/min, increase PEEP to 15 cm H2O. c. Increase VT to 550 mL, decrease f to 8 breaths/min, increase PEEP to 10 cm H2O. d. Decrease VT to 400 mL, decrease f to 8 breaths/min, decrease PEEP to 3 cm H2O.

For which of these patients would activated charcoal be indicated given the type of poisoning?

A) A 24-year-old female who was sniffing glue and now complains of a headache B) A 17-year-old male who drank bleach 30 minutes ago C) A 27-year-old who intentionally took a large amount of Tylenol 45 minutes ago D) A 53-year-old female who took an overdose of antidepressants earlier in the day