Fred, a lipid-soluble drug molecule, has just been swallowed by a human. Trace Fred's likely routes through the body and describe what is likely to happen to Fred by the time he leaves the humans' body
What will be an ideal response?
Before being absorbed from the GI tract into the blood stream, Fred may be metabolized into a different molecule. Once into the blood stream of the portal system, Fred would have to pass through the liver, where he could also be metabolized, before entering the general circulatory system. Once in the general circulatory system, Fred would likely travel to various tissues, and if sufficiently lipid soluble pass into and out of the brain. At some point Fred would likely be metabolized into a water soluble (ionized) molecule, pass in to the kidneys and the urine, where he would be excreted. Fred could still be lipid soluble and get dumped into the bile ducts, where he would get deposited into the feces, where he could be excreted.
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The frequency of a class interval plus the frequencies of all lower class intervals is the _____
grouped frequency of a distribution. a. simple b. summed c. cumulative d. relative
Which of the following statements is true of the development of the adolescent brain?
A. Adolescents display strong cognitive skills to control their impulses effectively because of the quick development of the prefrontal cortex. B. In adolescents, brain changes first occur at the subcortical level in the limbic system. C. The developmental disjunction in the brain accounts for reduced risk-taking behaviors in adolescents. D. In comparison with adults, adolescents display fewer emotions because of the slow growth of the amygdala and prefrontal cortex.