Which test will rise first after successful treatment for iron deficiency?
a. Reticulocyte count
b. Ferritin
c. MCV
d. Hemoglobin
ANS: A
The reticulocyte count will begin to increase within 5 to 7 days after institution of therapy. Hemoglobin will take roughly 2 months to return to normal, although it will begin to slowly increase within 2 weeks. The MCV will rise more slowly, as the microcytic red cells in circulation have to live out their normal life span; they will gradually be replaced with more and more normocytic red cells. Ferritin will be the last to rise; only after the erythron has been restored to normal will there be any excess iron to go to stores.
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