Most often the clinician makes a diagnosis of infectious mononucleosis by which of the following findings?
a. Significant lymphocytosis, with reactive lymphocytes predominating
b. Presence of mild thrombocytopenia, with a significant lymphocytosis
c. Demonstration of the presence of the heterophil antibody
d. Demonstration of the presence of cytomegalovirus antibody
ANS: C
Performing a test for the presence of the heterophil antibody is used to diagnose infectious mononucleosis. If this test is negative and the clinician is highly suspicious of the diagnosis, then tests for more specific Epstein-Barr virus antibodies may be necessary.
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