What is the primary pathologic change that occurs in interstitial lung disease?
a. Alveolar-capillary membrane structures replaced by fibrotic tissue
b. Bronchial submucosal gland hypertrophy
c. Bronchoconstriction of medium to small airways
d. Increased sputum production
ANS: A
The lung must respond to the damage and repair itself. If the exposure to the causative agent per-sists or if the repair process is imperfect, the lung may be permanently damaged with increased interstitial tissue replacing the normal capillaries, alveoli, and healthy interstitium.
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