A diagnosis of CLL requires morphologic and phenotypic findings of which of the following?

a. Variable absolute lymphocyte counts with few prolymphocytes and CD38+
b. Sustained absolute lymphocyte counts with mature lymphocytes, few prolymphocytes, smudge cells, CD20+, and ZAP-70+
c. Marked absolute lymphocytosis, anemia, and thrombocytopenia; prolymphocytes less than 10%
d. Sustained absolute lymphocyte counts; mature lymphocytes; CD3?, CD2+, CD4?, CD8?, CD7+, CD16+, CD56+/CD57?

Correct Answer: B