Duccio and Giotto were two artists whose innovations in ________ greatly influenced Renaissance painting styles

A. basing their works on religious traditions
B. introducing a flat, decorative space
C. exploring classical subject matter
D. creating figures and settings with an increased naturalism
E. Gothic sculpture

D
Duccio and Giotto were influential in making the shift from art styles of the Middle Ages to the quite different styles of the Renaissance.