Which of the following responses are potential adverse effects of ?2 agonists? I. ventilation-perfusion mismatch II. tachycardia III. metabolic effects IV. muscle tremor
A. I, II only
B. I, III, IV only
C. II, III, IV only
D. I, II, III, IV
?ANS: D
A. Incorrect response: See explanation D.
B. Incorrect response: See explanation D.
C. Incorrect response: See explanation D.
D. Correct response: β2 receptors in skeletal muscles are stimulated by β2 agonists, causing muscle tremors. Pulmonary vasodilatation in blood vessels previously constricted shunts blood to poorly perfused alveoli, causing the Pao2 to decrease. β1 receptors of the myocardium are stimulated by β2 agonists, causing tachycardia. β2 adrenergic bronchodilators can increase blood glucose and insulin levels, and decrease serum potassium concentrations.
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