Explain the major differences between Hodgkin and non-Hodgkin lymphomas
What will be an ideal response?
Answer: Hodgkin lymphoma:
Stage: localized
Distribution: central nodes
Mode of spread: contiguous
Extranodal disease: uncommon
PB: never involved
Cell type: abnormal bizarre cells
Treatment regimen: often ABVD
Non-Hodgkin lymphoma:
Stage: widespread
Distribution: peripheral nodes
Mode of spread: noncontiguous
Extranodal disease: common
PB: can be involved
Cell type: resembles normal lymphoid cells
Treatment regimen: often CHOP
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What is the major change the WHO made to the classifications of the myelodysplastic syndromes?
a. Dropped the 5q syndrome from myleodysplastic syndromes b. Reduced the percentage of blasts required for the diagnosis of acute myeloid leukemia from 30% to 20% c. Recognized acute myeloid leukemia as one of the myleodysplastic syndromes d. Created a new classification placing refractory anemia and the myeloproliferative disorders together
Hyperalbuminemia is caused by:
A. Dehydration syndromes. B. Liver disease. C. Burns. D. Gastroenteropathy.