If a patient who generates an intrapleural pressure of -4 mmHg to inhale 450 mL experiences inflammation and bronchospasm that reduce the radius of the bronchial airways to one-half of their original size, what pressure must the patient generate to inhale the same tidal volume?

a. 16 mm Hg c. 20 mm Hg
b. 64 mm Hg d. 48 mm Hg

b. 64 mm Hg