What are three neuro- or psycho-pharmacological features of the monoamine-related hallucinogens that distinguish them from the cannabinoid hallucinogens like delta-9-THC?
What will be an ideal response?
Monoamine-related hallucinogens P/P/Hs act through 5-HT receptors whereas cannabinoids act on anandimide receptors. Monoamine-related hallucinogens are generally more potent in inducing hallucinatory and kaleidoscopic experiences than cannabinoids. Monoamine-related hallucinogens increase psychological and physiological signs of arousal, whereas cannabinoids tend to decrease these. Cannabinoids have a generalized fluidizing action on neuronal membranes that is not a property of Monoamine-related hallucinogens. Cannabinoids are much more lipid soluble than Monoamine-related hallucinogens and are stored in fat tissue for several weeks. Tolerance to the subjective effects of Monoamine-related hallucinogens occurs fairly rapidly, whereas they do not show as rapid a tolerance with cannabinoids. Chronic use of cannabinoids can result in mild physical dependence, whereas there is no evidence of this with Monoamine-related hallucinogens.
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Fred has an IQ of 65 and cannot do schoolwork. He lives on the streets by begging, is usually dirty, and is always hungry. He would MOST likely be diagnosed with:
A) depression B) dyslexic. C) schizophrenic. D) mentally retarded.
When the victim of bullying develops a close or gratifying friendship,
A) the new friend is often ostracized by other children. B) the children are more likely to team up and retaliate against the bully. C) the bully often targets the new friend. D) bullying often comes to an end.