Cellulose acetate is performed on a patient with known homozygous Hb S who has received red cell transfusions in the past week. What hemoglobins would be expected to be found?

a. Hb S and Hb F
b. Hb A and Hb F
c. Hb S, Hb A, and Hb F
d. Hb S, Hb A, Hb F, and Hb A2

ANS: D
Hb S, Hb A, Hb F, and Hb A2 would be seen. Hb A, which is not present in patients with homozygous Hb S, is from the transfused red cells. Hb F and Hb A2 are normal hemoglobins.