The PAO2 depends on which of the following factors?
1. Ambient (atmospheric) pressure
2. Fractional concentration of inspired O2
3. Level of VA
4. Types of fuels burned (fat, protein, and carbohydrate)
a. 1, 2, and 3 only
b. 1 and 2 only
c. 3 only
d. 1, 2, 3, and 4
ANS: D
PAO2 = FiO2 ? (PB – 47) – PACO2 ÷ 0.8
where FiO2 is fraction of inspired oxygen, PB is barometric pressure, 47 is water vapor tension (in mm Hg) at 37° C, PACO2 is alveolar PCO2, and 0.8 is normal respiratory exchange ratio (R). As the A is the primary determinant of PACO2 any changes in A will affect the PAO2. Likewise the fuel source will determine the RQ which is normally 0.8.
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