For maintenance administration of bronchodilators to an adult patient with adequate inspiratory flow, which of the following aerosol drug delivery devices would you recommend?
1. Pressurized metered dose inhaler (pMDI)
2. Small-volume jet nebulizer
3. Dry powder inhaler
4. pMDI and holding chamber
a. 1 or 2 only
b. 2 or 3 only
c. 2 or 4 only
d. 3 or 4 only
ANS: D
For administration of maintenance therapy bronchodilators and antiinflammatory agents to adults, a pMDI with a valved holding chamber is the most convenient, versatile, and cost-effective approach. Dry powder inhalers are gaining popularity as an equivalent to pMDIs for maintenance therapy with available drugs for patients capable of generating adequate inspir-atory flow.
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