Name at least two pitfalls in immunophenotyping mature lymphoid malignancies, and explain how you would correct this
What will be an ideal response?
Answer: Some malignant B- cell lymphoproliferative disorders lack surface immunoglobulin and can be overlooked. Some lack surface antigens or an abnormal phenotype. Hodgkin lymphoma not only lacks many lymphoid cell antigens but also the neoplastic cells are rare, and a single cell suspension could be difficult to prepare because of fibrosis. Some abnormal phenotypes are not specific for a particular lymphoid neoplasm. It is important to use morphology together with immunophenotyping to help overcome these pitfalls.
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An alert and oriented 45-year-old female patient is complaining of shortness of breath. Although her respiratory volume and rate are satisfactory, you note cyanosis in her fingertips. Which one of the following should be your next action?
A) Administer supplemental oxygen. B) Assist respirations with the bag-valve mask. C) Place a nasopharyngeal airway and assist respirations. D) Move to the stretcher for immediate and rapid transport.
Pain in the RUQ may be a symptom of appendicitis
Indicate whether the statement is true or false