Which of the following mechanisms ultimately leads to ARDS regardless of the etiology?
a. Disruption of the endothelial and epitheli-al barriers
b. Alveolar flooding
c. Interstitial damage
d. Increased oncotic pressure
ANS: A
Although many seemingly unrelated risk factors for ARDS have been identified, all causes of ARDS evoke disruption of endothelial and epithelial barriers and typically occur under condi-tions associated with widespread microvascular injury to the lungs.
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