Describe the immunologic features and functions of NK cells
What will be an ideal response?
Answer: NK cells are effector cells of innate immunity, not adaptive immunity. Their main function is to kill infected cells and to activate macrophages to destroy phagocytosed microbes. Their CD markers are not characteristic of either T or B cells. They have a diversity of receptors that allow them to recognize appropriate target cells and destroy them. NK cells are positive for CD56 and CD16 (the Fcγ receptor III for IgG) and can recognize and attack pathogens with attached IgG via their IgG receptor (CD16).
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