Both anemia and carbon monoxide (CO) poisoning can cause severe hypoxia, yet neither condi-tion results in a major stimulation of breathing. Why is this so?

a. The peripheral chemoreceptors do not re-spond to low O2 content.
b. Anemia and CO poisoning depresses the peripheral chemoreceptors.
c. Anemia and CO poisoning depresses the central chemoreceptors.
d. Anemia and CO cause stagnant hypoxia, not hypoxemia.

ANS: A
Because of their extremely high blood-flow rates, the carotid bodies respond to decreased arterial partial pressure of O2 rather than to an actual decrease in arterial O2 content.

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