Which of the following differentiates an AL and an MPN?

a. The cells in an MPN are dysplastic, but morphology is normal in an AL.
b. Patients present with leukocytosis and mostly mature cells in AL, whereas blasts predominate in MPNs.
c. MPNs are defined by a bone marrow blast count of at least 20%.
d. A defining characteristic of ALs is that the cell of origin acquires the ability to proliferate continuously and demonstrates arrested development.

Correct Answer: D

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