Overdistention of the lungs causes the release of which inflammatory mediators?
a. Cytokines
b. Alpha-1 antitrypsin
c. Histamine
d. Macrophages
ANS: A
Overdistention of the lungs causes the release of inflammatory mediators such as cytokines, tu-mor necrosis factor, platelet-activating factor, thromboxane-B2, tumor necrosis factor alpha, and interleukin-1B. Macrophages are the actual source of some of these mediators.
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