What are the abnormal cytoplasmic inclusions in Chédiak-Higashi?
a. Nuclear fragments that prevent cell division
b. Ribosomal material that looks like Döhle bodies
c. Fused granules that inhibit bactericidal functions
d. Mucopolysaccharide lipids that disrupt cell function
ANS: C
Abnormally large fused granules that are peroxidase positive are seen in Chédiak-Higashi syndrome. Uncontrolled activity of the granular membrane creates large primary, secondary, and mixed primary/secondary granules. These inhibit the normal bactericidal function of these granules so that patients are susceptible to bacterial infection.
You might also like to view...
When you percuss the chest and hear hyperresonance, the patient may have a:
A) cardiac tamponade. B) hemothorax. C) pulmonary contusion. D) pneumothorax.
The effect of the Olmsteadruling on services for individuals with intellectual disabilities has been _________________________.?
A) an increase in community-based services B) ?an increase in institutional-based services C) a decrease in services available to individuals D) ?a decrease in individuals requiring services