Explain how EPO regulates RBC production
What will be an ideal response?
Answer: Erythropoiesis is governed by a negative feedback mechanism centered on hypoxic conditions. Hypoxia stimulates synthesis of EPO by the kidney. When erythropoiesis is sufficient to correct the hypoxia, the negative feedback is shut off. This is done by downregulating kidney synthesis of EPO.
Health Professions
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Most patients appreciate it when a health care worker can speak even a few words of their language
Indicate whether the statement is true or false
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