Explain the biochemistry involved in platelet function

What will be an ideal response?

Answer:
 Platelets become activated as a result of the subendothelial collagen  (a) Flat, discoid shape  spiked appearance (b) actin and myosin go from a random arrangement to a parallel arrangement; (c) tubulin forms a circumferential band around the organelle zone to assist in expelling granular contents to the surface of the platelets.
 Activated platelets adhere to subendothelial collagen with the help of VWF and GP Ib/IX.
 Once adhesion takes place, more platelets are recruited to the site and aggregation begins. Substances needed for platelet aggregation: fibrinogen and GP IIb/IIIa.
 Platelets secrete their granular contents and initiate secondary hemostasis.