Which of the following is a common feature of the myelodysplastic syndromes?
a. Peripheral blasts between 5% and 20%
b. Progressive cytopenias and dyspoiesis in one or more cell lines
c. Macrocytic red cells and leukocytosis
d. Low mean cell volume (MCV) and thrombocytopenia
ANS: B
Progressive cytopenias and dyspoiesis in one or more cell lines is characteristic of myelodysplastic syndromes. Although blasts may be increased in the peripheral blood, they are generally less than 5%. Macrocytic red cells may be present so that the MCV may be elevated; however, the white count is usually normal or decreased (depends on type), and platelets are normal to decreased.
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