What stimulates production of erythropoietin?
a. Decreased red cell number in the bone marrow
b. Increased peripheral red cell number
c. Decreased iron stores
d. Decreased oxygen level in tissue
ANS: D
Peritubular cells in the kidney detect too little oxygen in tissue (also called hypoxia). They then synthesize erythropoietin. This increases red cell production in the bone marrow, unless the marrow is unable to respond to respond to the erythropoietin stimulus.
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